Domestic Birds as Carriers of Cryptococcus neoformans, the Main Cause of the Life Threatening Human Systemic Cryptococcosis

Document Type : Original Article

Author

Botany Department, Faculty of Science, Suez Canal University, 41522 Ismailia, Egypt

Abstract

Samples of bird excreta including domestic pigeons were collected from farmer houses and aviary
shops in rural and urban areas of Ismailia. The collected samples were mycologically processed for the
occurrence of the pathogenic yeast, Cryptococcus neoformans. It was isolated mainly from pigeon
excreta and from only one sample of colored birds excreta collected from decorated colored bird's
shops. Pigeon excreta positive for Cryptococcus neoformans were suspended in sterilized phosphate
buffered saline then three different doses of the supernatant were interaperitoneally injected into groups
of experimental albino mice to assess its dissemination and the various pathological effects resulting
from systemic infection. Mainly, pulmonary and occasional meningeal lesions were evident in the
infected mice.

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