A series of novel 2-aminothiazole derivatives (3a-e) has been synthesized by the reaction of 4-[4- methoxy-3-methylphenyl]-4-oxobutenoic acid (1) with thiourea derivatives (2a-e). The thiazolopyridazine derivatives (4a-c) and (5) were obtained from the reaction of 4-hydroxy-1,3-thiazole (3a-e) with hydrazine and phenylhydrazine, respectively. The behavior of the 4-hydroxy-1,3-thiazole (3a-e) toward acetic anhydride and bromine was also studied. The proposed structures of the products were based on microanalytical and spectroscopic data.
El-Sakka, S., Soliman, M., & Abdullah, R. (2013). Synthesis and Reactions of Some Thiazole Derivatives. Catrina: The International Journal of Environmental Sciences, 8(1), 1-4. doi: 10.12816/0010669
MLA
Sahar El-Sakka; Mohamed Soliman; Rokaia Abdullah. "Synthesis and Reactions of Some Thiazole Derivatives". Catrina: The International Journal of Environmental Sciences, 8, 1, 2013, 1-4. doi: 10.12816/0010669
HARVARD
El-Sakka, S., Soliman, M., Abdullah, R. (2013). 'Synthesis and Reactions of Some Thiazole Derivatives', Catrina: The International Journal of Environmental Sciences, 8(1), pp. 1-4. doi: 10.12816/0010669
VANCOUVER
El-Sakka, S., Soliman, M., Abdullah, R. Synthesis and Reactions of Some Thiazole Derivatives. Catrina: The International Journal of Environmental Sciences, 2013; 8(1): 1-4. doi: 10.12816/0010669